Archive for the 'PD: models and applications' Category

21-07-08(19:17:55)

Tuesday, July 22nd, 2008

Authors:
Bernard L. Schneider
Meret N. Gaugler
Samareh Azeredo da Silveira Lajaunias
Jean-Charles Bensadoun
Patrick Aebischer

Institutions:
Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

Title of abstract : Viral vectors for modeling and treating Parkinson disease
Abstract text:
In order to develop effective neuroprotective strategies for Parkinson disease (PD), it appears essential to understand the interplay between multiple genes involved in [...]

17-07-08(13:15:55)

Thursday, July 17th, 2008

Authors:
Büchele F 1, Papazoglou A 1, Jiang W 1, Garcia J 1, Nikkhah G 1

Institutions:
Department of Stereotactic Neurosurgery, Laboratory of Molecular Neurosurgery, Neurocentre, University Hospital Freiburg, Breisacher Str. 64, 79106 Freiburg, Germany

Title of abstract : Two-strep grafting – a new method to enhance cell survival and study graft development in a rat model of Parkinson’s [...]

15-07-08(23:11:20)

Wednesday, July 16th, 2008

Authors:
Rath A 1, Papazoglou A 1, Hackl C 1, Klein A 1, Nikkhah G 1

Institutions:
1 Department of Stereotactic Neurosurgery, Laboratory of Molecular Neurosurgery, Neurocentre, University Hospital Freiburg
Breisacher Str. 64
79106 Freiburg
Germany

Title of abstract : Effects of Two-Step-Grafting on the survival of embryonal (E14) mesencephalic dopaminergic neurons and on the striatal reinnervation in a rat model of [...]

15-07-08(22:24:02)

Wednesday, July 16th, 2008

Authors:
Krause M 1, Papazoglou A 1, Ganser C 1, Nikkhah G 1, Kobayashi E 2

Institutions:
1 Stereotactic Neurosurgery, Laboratory of Molecular Neurosurgery, Neurocentre, University Hospital Freiburg, Breisacher Str. 64, 79106 Freiburg, Germany
2 Division of Organ Replacement Research, Center for Molecular Medicine, Jichi Medical School, Tochigi 329-0498, Japan

Title of abstract : Green Fluorescent Protein (GFP) transgenic rats: [...]

15-07-08(21:51:46)

Wednesday, July 16th, 2008

Authors:
Capetian P 1,2
Krause M 2
Papazoglou A 2
Ditter M 1
Nikkhah G 2

Institutions:
1 Department of Neuropahtology, University clinic Freiburg
2 Department of Stereotactic Neurosurgery, University clinic Freiburg

Title of abstract : Inducible conditional ablation of transgenic intracerebral fetal tissue grafts
Abstract text:
Intracerebral grafting of fetal tissue is a well established model and able to ameliorate symptoms in many animal models [...]

15-07-08(19:59:58)

Wednesday, July 16th, 2008

Authors:
I. Mendez and the Halifax Neuraltransplantation Team

Institutions:
Brain Repair Centre, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada, B3H 3A7

Title of abstract : CLINICAL NEURALTRANSPLANTATION FOR PARKINSON’S DISEASE: METHODOLOGICAL CONSIDERATIONS
Abstract text:
The success of cell restorative strategies to repair the brain in neurodegenerative conditions such as Parkinson’s disease may depend on our ability [...]

15-07-08(18:42:36)

Wednesday, July 16th, 2008

Authors:
Hans Lafford, Quinton Jones, Anna-Marie Szczesniak and Harold A. Robertson
Institutions:
Brain Repair Centre, Dalhousie University, Canada
Title of abstract : do intrinsic dopamine neurons in striatum account for the neuropathology observed in some long-term fetal neuronal grafts?
Abstract text:
Controversy has emerged following studies reporting that fetal ventral mesencephalic neurons transplanted to the striatum in patients with Parkinson’s disease [...]

15-07-08(18:39:59)

Wednesday, July 16th, 2008

Authors:
Stirl K 1; Freudenberg U 3; Hermann A 1,2; Welzel PB 3; Schwarz SC 4; Grimmer M 3; Zieris A 3; Panayanuwat W 3; Zschoche S 3; Werner C 3; Storch A 1,2

Institutions:
1 Department of Neurology, Dresden University of Technology, Dresden; 2 Center for Regenerative Therapies Dresden (CRTD), Dresden; 3 Leibniz Institute of Polymer Research [...]

15-07-08(17:39:31)

Wednesday, July 16th, 2008

Authors:
Schreglmann SR 1,2
Winner B 1
Rockenstein E 3
Winkler J 3,4
Masliah E 3
Fred H. Gage 1

Institutions:
1 The Salk Institute for Biological Studies, La Jolla, CA
2 Department of Neurology, University of Regensburg, Regensburg
3 Department of Neurosciences, UCSD, San Diego, CA
4 Section Molecular Neurology, University of Erlangen, Erlangen

Title of abstract : The effect of human alpha-Synuclein on adult hippocampal [...]

15-07-08(16:44:32)

Tuesday, July 15th, 2008

Authors:
Paumier KL, Sortwell CE, Daley BF, Terpstra BT, Madhavan LM, Levine ND, Hemmerle AM, Dickerson JW, Seroogy KB and Collier TJ.

Institutions:
Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 USA.

Title of abstract : Chronic antidepressant treatment protects nigral dopamine neurons in a rat model of Parkinson’s disease
Abstract text:
There is considerable evidence that Parkinson’s disease (PD) [...]