Archive for the 'PD: models and applications' Category

25-07-08(14:41:52)

Friday, July 25th, 2008

Authors:
Tomas Björklund1, Ludovic Leriche2, Nathalie Breysse1, Laurent Besret2 , Marie-Claude Grégoire2, Thomas Carlsson1, Frédéric Dollé3, Ronald J Mandel4, Nicole Déglon2, Philippe Hantraye2 and Deniz Kirik1

Institutions:
1 B.R.A.I.N.S Unit, BMC D11, Department of Experimental Medical Science, Lund University, Sweden; 2 URA CEA/CNRS 2210, MIRCen, France; 3 Laboratoire d’Imagerie Moléculaire Expérimentale, CEA, Orsay, France; 4 Department of Neuroscience, [...]

24-07-08(20:23:34)

Friday, July 25th, 2008

Authors:
Ole Isacson1, Ivar Mendez2, Angel Viñuela1, Arnar Astradsson1, Penelope Hallett1, Karim Mukhida2, Harold Robertson2, Travis Tierney1, Renn Holness2, Alain Dagher3 and John Q. Trojanowski4

Institutions:
1 Harvard University and McLean Hospital, NINDS Udall Parkinson’s Disease Research Center of Excellence, Boston, MA 02478, USA; 2 Dalhousie University and Queen Elizabeth II Health Sciences Centre, Division of Neurosurgery [...]

24-07-08(18:10:03)

Thursday, July 24th, 2008

Authors:
Roger Barker

Institutions:
Cambridge Centre for Brain Repair, University of Cambridge, Forvie Site, Cambridge, CB2 2PY, United Kingdom

Title of abstract : Can cell therapies really ever help treat Parkinson’s disease?
Abstract text:
Parkinson’s disease (PD) is a common neurodegenerative disorder that typically presents later in life with a combination of motor abnormalities along with affective, cognitive and autonomic disturbances. [...]

24-07-08(18:04:38)

Thursday, July 24th, 2008

Authors:
*M. CARTA1, A. MUÑOZ1, Q. LI2, F. GARDONI3, E. MARCELLO3, T. CARLSSON1, C. QIN2, D. KIRIK1, M. DI LUCA3, A. BJÖRKLUND1, E. BEZARD4

Institutions:
1Wallenberg Neuroscience Center, Lund, Sweden; 2China Academy of Medical Science, Beijing, China; 3University of Milano, Milano, Italy; 4University Victor Segalen Bordeaux, Bordeaux, France

Title of abstract : Serotonin autoreceptor agonists for the treatment of [...]

24-07-08(16:35:52)

Thursday, July 24th, 2008

Authors:
Freeman TB 1; Cicchetti F 4; Saporta S 2; Hauser R 3; Olanow CW 5; Saint-Pierre M 4; Chu Y 6; Kordower JH 6

Institutions:
Department of Neurosurgery 1, Department of Anatomy 2, Department of Anatomy 3 University of South Florida; Centre de rescherche due CHUL 4; Mt. Sinai Medical Center 5; Rush University Medical Center 6

Title [...]

24-07-08(12:28:56)

Thursday, July 24th, 2008

Authors:
Gonzalez-Aparicio R, Fernandez-Espejo E
Institutions:
Departamento de Fisiologia Medica y Biofisica, Universidad de Sevilla, 41009 Sevilla, Spain.
Title of abstract : Improved trophic efficacy of GDNF after combination with TGF-beta1 both in vitro and in vivo models of parkinsonism
Abstract text:
The objectives were: i) to analyze the trophic effects of GDNF, TGFbeta1 and combination of both in a [...]

24-07-08(0:14:35)

Thursday, July 24th, 2008

Authors:
Herrmann J 1,2, Timmer M 3, Lundblad M 4, Cenci A 4, Nikkhah G 3, Winkler C 2

Institutions:
1. Department of Neurology, Hannover Medical School, Hannover, Germany
2. Department of Neurology, University of Freiburg, Freiburg, Germany
3. Department of Stereotaxic Neurosurgery, University of Freiburg, Freiburg, Germany
4. Department of Experimental Medical Science, University of Lund, Lund, Sweden

Title of abstract [...]

24-07-08(0:05:50)

Thursday, July 24th, 2008

Authors:
Winkler C

Institutions:
Department of Neurology, University of Freiburg, Freiburg, Germany

Title of abstract : Dopamine-dependent dyskinesia: Role of dopaminergic and serotonergic transplants
Abstract text:
Transplantation of fetal ventral mesencephalic tissue in Parkinson’s disease has given variable results. While some patients have shown substantial recovery in motor function, others have shown no improvement and even a worsening of dyskinesia. Recent [...]

23-07-08(14:39:46)

Wednesday, July 23rd, 2008

Authors:
Fernandez-Espejo E 1, Galan-Rodriguez B 1, del-Marco A 1, Ramiro-Fuentes S 1, Gonzalez-Aparicio R 1, Tunez I 2, Tasset I 2

Institutions:
1. Departamento de Fisiologia Medica y Biofisica, Universidad de Sevilla, 41009 Sevilla, Spain.
2. Departamento de Bioquimica y Biologia Molecular, Universidad de Cordoba, Av. Menendez Pidal s/n, 14004 Cordoba, Spain.

Title of abstract : Antiparkinsonian trophic [...]

21-07-08(23:40:02)

Tuesday, July 22nd, 2008

Authors:
Bakay RAE,Smith AP,Kelly LP,Newman MB

Institutions:
Departments of Neurosurgery1, Rush University Medical Center, 1735 W. Harrison St. Cohn Research Building, Suite 406, Chicago, IL 60612.

Title of abstract : Therapeutic Use of Human Embryonic Stem Cells (hESC) and Human Umbilical Cord Blood (hUCB) Stem Cell in Parkinson’s Disease Model.
Abstract text:
The present study was designed to determine the [...]