Archive for the 'HD: clinical applications' Category

20-08-08(16:06:24)

Wednesday, August 20th, 2008

Authors:
Urbach, YK 1
Raber, KA 1
von Horsten, S 1

Institutions:
1 Friedrich-Alexander-University of Erlangen-Nuremberg, Franz-Penzoldt-Center, Experimental Therapy, Erlangen, Germany

Title of abstract : Differential effects of environmental enrichment by voluntary wheel running on Huntington’s transgenic rats as detected by automated phenotyping technology
Abstract text:
The PhenoMaster system (TSE Systems, Germany) is a modular, multi-purpose tool for the investigation of multidimensional physiobehavioral [...]

20-08-08(15:26:19)

Wednesday, August 20th, 2008

Authors:
Raber KA 1
Urbach YK 1
Stephan M 2
Nguyen HP 3
Riess O 3
von Horsten S 1

Institutions:
1 Franz-Penzoldt-Center, Section of Experimental Therapy, University of Erlangen-Nürnberg, Palmsanlage 5, 91054 Erlangen, Germany
2 Dept. of Functional and Applied Anatomy, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany
3 Dept. of Medical Genetics, University of Tuebingen, Calwerstr. 7, 72076 Tuebingen, Germany

Title of abstract [...]

15-07-08(13:34:33)

Tuesday, July 15th, 2008

Authors:
Jiang W.1, Döbrössy M.1, Papazoglou A.1, Büchele F.1, Diaconu O.1, Garcia J.1, Nikkhah G.1
Institutions:
1 Stereotactic Neurosurgery, Laboratory of Molecular Neurosurgery, Neurocentre, University Hospital Freiburg, Freiburg, Germany
Title of abstract : Micro-transplantation approach in a quinolinic acid induced rodent model of Huntington’s disease
Abstract text:
Neural transplantation has been demonstrated to be an optional treatment for Huntington’s disease (HD). [...]

14-07-08(10:37:38)

Monday, July 14th, 2008

Authors:
Kelly, C.M.1, Precious, S.V.1, Lane, E.1, Scherf, C. 2, Williams, D. 2, Torres, E., Weyrauch, U. 1, Daly, C. 1, Baird, A. 1, Penketh, R. 2, Amso, N.N. 2, Dunnett, S.B. 1, Rosser, A.E. 1,3

Institutions:
1 Brain Repair Group, School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3US.
2 Department of Obstetrics and Gynaecology, School of [...]

09-07-08(18:59:12)

Thursday, July 10th, 2008

Authors:
Paola Piccini

Institutions:
Division of Neuroscience
Imperial College London, UK

Title of abstract : Recent functional imaging in Huntington’s disease
Abstract text:
The functional imaging technique of positron emission tomography (PET) has been used to study regional brain function in Huntington’s disease (HD) in vivo for more than a decade. Reduced striatal glucose metabolism (assessed with 18FDG) and dopamine receptor binding [...]

08-07-08(9:44:35)

Tuesday, July 8th, 2008

Authors:
Döbrössy MD

Institutions:
Stereotactic Neurosurgery, Neurozentrum, Universitätsklinikum, Breisacher Str. 64, 79106 Freiburg, Germany

Title of abstract : Environmental and experience-dependent graft plasticity and functional recovery in a rodent HD model
Abstract text:
The objective of cell replacement therapy is to repair the nervous system by introducing new cells that can replace the function of the compromised or lost cells. The [...]

26-06-08(14:27:43)

Thursday, June 26th, 2008

Authors:
Mazurová Y 1, Guncová I 1, Rudolf E 2, Látr I 3
Institutions:
1Dept. of Histology and Embryology and 2Dept. of Medical Biology and Genetics, Charles University in Prague, Faculty of Medicine in Hradec Králové, 3Neurosurgery Clinic, Faculty Hospital, Hradec Králové - Czech Republic
Title of abstract : Huntington’s disease model: Compartmentalization of neurogenic niche in response to [...]

03-06-08(2:52:39)

Wednesday, June 4th, 2008

Authors:
Franich NR 1, Fitzsimons HL 2, Klugmann M 3, During MJ 1,4, and Young D 1,5

Institutions:
1. Department of Molecular Medicine & Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
2. Neurologix Inc., Fort Lee, New Jersey, USA
3. Department of Physiological Chemistry, Johannes Gutenberg University, Mainz, Germany
4. Department of Molecular Virology, [...]