Authors:
Abrous DN
Institutions:
INSERM U862, Magendie Neurocenter, Bordeaux, France
Title of abstract : Adult hippocampal neurogenesis and spatial memory
Abstract text:
The dentate gyrus (DG) of the hippocampus is one of the few regions of the mammalian brain where new neurons are generated throughout adulthood. This structure is part of an integrated network that plays an important role in memory [...]
Authors:
1Armin Blesch, Ph.D., 1Leon Thal, M.D., 1Mary Pay, R.N., 1David Salmon, Ph.D., 1Adam Fleischer, M.D., 1David Barba, M.D., 2Zoe Arvanitakis, M.D., 2David Bennett, M.D., 3Roy Bakay, M.D., 4Steve Potkin, M.D., 5Kathie Bishop, Ph.D., 5Mehdi Gasmi, Ph.D., 1James Conner, Ph.D., 5Raymond Bartus, Ph.D., 1Mark H. Tuszynski, M.D., Ph.D.
Institutions:
Departments of 1Neurosciences, University of California-San Diego, 2Neurology and [...]
Authors:
Mufson EJ
Institutions:
Rush University Medical Center
Title of abstract : Cholinotrophic Dysfunction in During the Progression of Alzheimer’s Disease
Abstract text:
The cholinergic cortical projection system requires the interaction of nerve growth factor (NGF) and it high (trkA) and low (p75NTR) affinity receptors for biological activity and is neurotrophic dependent neural axis is vulnerable in Alzheimer’s disease (AD). The [...]
Authors:
Bjugstad KB 1, Cornelius SK 1, Snyder EY 2, MacLean K 1
Institutions:
1. Dept. Pediatrics, Univ Colorado Denver, Aurora, CO;
2. Burnham Institute, La Jolla, CA
Title of abstract : Neural stem cells as a potential treatment for Down syndrome using young and aged trisomic Ts65Dn mice
Abstract text:
Individuals with Down syndrome (DS) are usually hit twice in their [...]
Authors:
Lockrow JP, Boger HA, Granholm AC
Institutions:
Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA.
Title of abstract : Locus coeruleus degeneration in a mouse model for Down syndrome: A potential stimulus for neuroinflammation
Abstract text:
Individuals with Down syndrome (DS), or trisomy 21, develop the neuropathological hallmarks of Alzheimer’s disease (AD), including amyloid deposition, cholinergic neuron [...]
Authors:
Freeman LR 1
Granholm AC 1,2
Institutions:
1 Department of Neuroscience, Medical University of South Carolina Charleston, SC
2 Center on Aging, Medical University of South Carolina Charleston, SC
Title of abstract : dietary fat and cholesterol effects on developing hippocampal grafts in oculo
Abstract text:
The “Western Diet”, containing high levels of saturated fat, hydrogenated fat (“trans fats”), and cholesterol is [...]
